In brief, at 1.0 rpm even highly susceptible subjects were symptom-free, or nearly so. At 3.0 rpm subjects experienced symptoms but were not significantly handicapped. At 5.4 rpm, only subjects with low susceptibility performed well and by the second day were almost free from symptoms. At 10 rpm, however, adaptation presented a challenging but interesting problem. Even pilots without a history of air sickness did not fully adapt in a period of twelve days.That sort of research is the basis for the present day recommendations of 1 to 3 rpm.
The Architecture of Artificial-Gravity Environments for Long-Duration Space Habitation